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Updated: Jul 15, 2026

Helical Organization of Blood Coagulation Factor VIII on Lipid Nanotubes
Published on: June 3, 2014
[Factor XIII deficiency in a newborn]
R Diehl1, S Thouvenin, J Reynaud
1Unité d'hématologie pédiatrique, CHU de Saint-Etienne, hôpital Nord, avenue Albert-Raimond, 42055 Saint-Etienne cedex 02, France.
Abstract:
Factor XIII deficiency is an uncommon inherited disorder which is characterized by umbilical cord bleeding and an unusually high incidence of intracranial hemorrhage. We report here a case of Factor XIII deficiency in a child that presented a caput. succedaneum as the first manifestation of the disease and then an umbilical cord bleeding. The importance of performing a quantitative FXIII assay in the presence of strong clinical suspicion is strengthened because of the normality of the standard screening tests and the important therapeutic consequences.
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