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Updated: Jul 15, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
A method of measuring anterior chamber volume using the anterior segment optical coherence tomographer and
Ningli Wang1, Bingsong Wang, Gaoshou Zhai
1Tongren Ophthalmic Center, Beijing Tongren Hospital, Capital University of Medical Sciences, Beijing, China. wbsod@vip.sina.com
Purpose:
To describe and evaluate a new method for measuring anterior chamber volume (ACV).
Design:
Observational case series.
Methods:
The authors measured ACV using the anterior chamber (AC) optical coherence tomographer (OCT) and applied image-processing software developed by them. Repeatability was evaluated. The ACV was measured in patient groups with normal ACs, shallow ACs, and deep ACs. The volume difference before and after laser peripheral iridotomy (LPI) was analyzed for the shallow and deep groups.
Results:
Coefficients of repeatability for intraoperator, interoperator, and interimage measurements were 0.406%, 0.958%, and 0.851%, respectively. The limits of agreement for intraoperator and interoperator measurement were -0.911 microl to 1.343 microl and -7.875 microl to -2.463 microl, respectively. There were significant ACV differences in normal, shallow, and deep AC eyes (P < .001) and before and after LPI in shallow AC (P < .001) and deep AC (P = .008) eyes.
Conclusions:
The ACV values obtained by this method were repeatable and in accord with clinical observation.
