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Updated: Jul 15, 2026

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
[Neonatal sepsis in the era of antenatal antibiotic prophylaxis]
José Luis Tapia I1, Cristina Reichhard T, M Isabel Saldías R
1Unidad de Neonatología, Departamento de Pediatría, Hospital Clínico, Pontificia Universidad Católica de Chile, Santiago, Chile. jlta@med.puc.cl
Abstract:
The aim of this study was to compare incidence, bacteriology and associated mortality of neonatal sepsis in a neonatal unit, after (2001-2004) and before (1995-1996) implementation of universal screening for prevention of Group B Streptococcus diseases. Early onset sepsis incidence decreased from 2.5 to 1 per 1000 live births (p=0.03), with a decrease in the proportion of Group B Streptococcus cases from a 54% to 11% (p<0.01). In late onset sepsis, coagulase-negative Staphylococci continued to be the predominant pathogen (49% of cases), and Candida albicans emerged as the second etiologic agent in the postscreening period. Sepsis associated mortality was low in both periods (2.2%).
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