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Updated: Jul 15, 2026

Systems Biology of Metabolic Regulation by Estrogen Receptor Signaling in Breast Cancer
10:36

Systems Biology of Metabolic Regulation by Estrogen Receptor Signaling in Breast Cancer

Published on: March 17, 2016

Estrogen receptor alpha polymorphisms and postmenopausal breast cancer risk

A M González-Zuloeta Ladd1, A Arias Vásquez, F Rivadeneira

  • 1Department of Epidemiology & Biostatistics, Erasmus MC, P.O. Box 2040, Rotterdam, 3000 CA, The Netherlands.

Breast Cancer Research and Treatment
|April 25, 2007
PubMed
Summary

Estrogen receptor alpha (ESR1) gene polymorphisms, specifically PvuII and XbaI, do not appear to increase breast cancer risk in Caucasian postmenopausal women. This finding is supported by an association study and a meta-analysis of published data.

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