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Updated: Jul 15, 2026
A Low Cost Setup for Behavioral Audiometry in Rodents
Published on: October 16, 2012
Severe acoustic trauma in adult rats induced by short duration high intensity sound
Ken Kojima1, Masahiro Matsumoto, Juichi Ito
1Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan. kojimaken@ent.kuhp.kyoto-u.ac.jp
Conclusion:
Short duration high intensity sound (SDHIS) induced severe functional damage in adult rats.
Objective:
Previous reports showed that SDHIS induced severe histological changes in the cochleae of guinea pigs. This study examined the hearing functions of rats exposed to SDHIS.
Materials And Methods:
Animals were exposed for 1 min to a 137 dB sound pressure level (SPL) broadband noise. Auditory functions of the experimental animals were assessed using an auditory brainstem response (ABR) measurement system at frequencies of 8, 16, and 32 kHz before and 14 days after exposure to SDHIS.
Results:
After SDHIS, none of the experimental animals showed any response when stimulated by maximum SPLs at all frequencies of our ABR system.
