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Acute otitis media in schoolchildren: allergic diseases and skin prick test positivity
Yngvild E Bentdal1, Per Nafstad, Gunnhild Karevold
1Department of Otorhinolaryngology, Faculty Division of Akershus University Hospital, University of Oslo, Sykehusvagen 27, 1478 Lørenskog, Norway. y.e.bentdal@medisin.uio.no
Insights
Children with allergies, particularly asthma, face a higher risk of acute otitis media (AOM). SPT-negative children with asthma or allergic rhinoconjunctivitis showed increased AOM risk, suggesting allergy management may impact AOM incidence.
Area of Science:
- Pediatrics
- Allergy and Immunology
- Epidemiology
Background:
- Acute otitis media (AOM) is a common childhood infection.
- Allergic diseases are prevalent in children and may influence AOM risk.
- Understanding the interplay between AOM and allergies is crucial for effective management.
Purpose of the Study:
- To investigate the association between AOM, allergic diseases, and skin prick test (SPT) positivity in 10-year-old children.
- To determine if SPT results modify the relationship between allergic diseases and AOM.
Main Methods:
- A population-based cross-sectional study involving 3406 10-year-old children.
- Questionnaires collected data on AOM episodes and physician-diagnosed allergic diseases.
- Skin prick testing was performed on 2657 children.
- Logistic regression analyses were used to assess associations and control for confounders.
Main Results:
- AOM was present in 13.8% of children; 4.1% experienced two or more episodes.
- A significant association was found between AOM and reported allergic diseases, especially asthma.
- SPT-negative children with asthma or allergic rhinoconjunctivitis had a notably increased risk of AOM.
Conclusions:
- Single and recurrent AOM episodes in 10-year-olds are linked to reported allergic conditions.
- SPT-negative children with asthma and allergic rhinoconjunctivitis exhibit a heightened risk for AOM.
- Optimizing the management of allergic symptoms may potentially reduce AOM incidence in school-aged children.
Conclusions:
Single and repeated episodes of acute otitis media (AOM) in 10-year-old children were associated with reported allergic disease. Further, skin prick test (SPT)-negative children with reported asthma and allergic rhinoconjunctivitis had increased risk of AOM. We suggest that optimal treatment of allergic symptoms may have an effect on AOM in school children.
Objective:
The objective of the study was to estimate associations between AOM, allergic diseases and SPT positivity in 10-year-old children.
Materials And Methods:
Population-based cross-sectional study of 3406 10-year-old children living in Oslo. Main outcome measures were questionnaire-based information on AOM and reported physician-diagnosed allergic diseases with symptoms during the last year. In addition, 2657 children were skin prick tested. Logistic regression analyses were performed to estimate associations and control for potential confounders.
Results:
One or more episodes of AOM were present in 13.8% (n=470) of the children; 9.7% (n=331) had single episodes, while 4.1% (n=139) had two or more infections. We found a statistically significant association between AOM and reported allergic diseases, strongest for AOM and asthma with odds ratio 2.7 (95% confidence interval 1.8-4.0) and 2.3 (95% confidence interval 1.3-4.3) for single and two or more episodes of AOM, respectively. The risk for AOM was increased in asthmatic SPT-negative children compared with asthmatic SPT-positive children, the odds ratios were 3.0 (1.7-5.4) and 1.5 (0.8-2.8), respectively. The same tendency was found for allergic rhinoconjunctivitis.
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