Related Experiment Video
Updated: Jul 15, 2026
Through-the-Wall Blood Sampling Method to Minimize Sleep Disruption in Clinical Settings
Published on: June 13, 2025
The impact of work on the night blood pressure dipping profile
Britt A Sjölin-Israelsson1, Inger E Enström
1Bergnäset Health Centre, 97223 Luleå, Sweden. britt.sjolin-israelsson@nll.se
Objective:
The purpose of this study was to elucidate whether ambulatory blood pressure (ABPM) performed during a work day and a non-work day had any impact on the night dipping profile.
Study Design:
A crossover randomized ABPM study in primary healthcare was retrospectively analysed for the occurrence of non-dipping (ND), dipping (D) or extreme (XD) nightly dipping. Non-dippers were defined as subjects with less than 10% and extreme dippers as subjects with more than 20% nightly blood pressure fall measured as mean arterial pressure (MAP).
Subjects:
Forty treated hypertensives and 40 normotensives (20 men and 20 women in each group), who had performed ABPM twice in a fortnight. They had been randomly allocated to perform a work day or a non-work day as the first period.
Result:
Only one of the 16 subjects who at any time was a non-dipper remained so during both monitoring periods. Extreme dipping was more often reproduced in nine persons out of 29. Of all 80 subjects, 43.8% (35 persons) remained dippers during both periods. No one changed from a non-dipper to an extreme dipper or the reverse. The odds of being an ND were 3.8 times more common on a non-work day, p = 0.010. XDs were slightly more common (1.7 times) on a work day than on a non-work day, p = 0.040. There was no correlation as to the degree of MAP and the dipping profile, p = 0.629.
Conclusions:
More subjects were non-dippers at the end than at the beginning of the work week. It is essential to consider this when attempting to identify a non-dipper by ABPM.
Related Concept Videos
01:17Measurement of Blood Pressure
01:30Alterations in Blood Pressure
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart beats)...
01:15Chronopharmacokinetics: Circadian Rhythms and Influence on Drug Response
The time of drug administration is an important factor to consider, as it can influence the toxic dose of a drug. For example, a study conducted by Prins et al. in 1997 examined the effects of the timing of...
01:28Factors affecting Blood pressure
Physiological Factors:
01:28Special considerations while measuring blood pressure
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
01:24Blood Pressure Imbalances and Circulatory Shock
Blood Pressure: Hypertension and Hypotension
Normal blood pressure is 120/80 mm Hg. Elevated blood pressure is 120-129/under 80 mm Hg. Hypertension, warranting treatment at 130/80 mm Hg, is often asymptomatic and can lead to severe cardiovascular events, aneurysms, peripheral arterial disease, chronic renal disease, or cardiac...