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Measuring activity patterns using actigraphy in multiple sclerosis.

Daphne Kos1, Guy Nagels, Marie B D'Hooghe

  • 1Department of Rehabilitation Research, Vrije Universiteit Brussel (VUB), Brussels, Belgium.

Chronobiology International
|April 25, 2007
PubMed
Summary

Actigraphy placement on the wrist or ankle provides similar activity data for multiple sclerosis (MS) patients and controls. Wrist placement is better tolerated, offering a practical method for assessing physical activity in MS.

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Area of Science:

  • Neurology
  • Rehabilitation Science
  • Biomedical Engineering

Background:

  • Multiple sclerosis (MS) is a central nervous system demyelinating disease causing significant motor and cognitive impairments.
  • Accurate assessment of daily activity patterns is crucial for managing MS and its functional limitations.
  • Self-report measures are common but may lack objectivity; actigraphy offers an objective alternative for activity monitoring.

Purpose of the Study:

  • To compare the efficacy and specificity of wrist versus ankle actigraphy for measuring physical activity in individuals with MS and healthy controls.
  • To investigate the correlation between subjective self-reported activity levels and objective actigraphy data.
  • To determine the optimal placement for actigraphy in MS patients for tolerability and data accuracy.

Main Methods:

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  • Nineteen individuals with MS and 10 healthy controls participated in the study.
  • Participants wore actigraphs on both the wrist and ankle for three consecutive days.
  • Concurrent self-report logs were maintained every 30 minutes to record performed activities.

Main Results:

  • Actigraphy data from wrist and ankle placements showed similar activity patterns during peak hours (9:00-20:30) in both MS patients and controls.
  • Wrist actigraphy was better tolerated by participants compared to ankle placement.
  • Actigraphy data demonstrated moderate correlations with self-reported activity (r=0.57 for ankle, r=0.59 for wrist), with self-reports explaining 44-50% of the variance in actigraphy data.

Conclusions:

  • Both wrist and ankle actigraphy yield comparable activity data in MS populations and healthy individuals.
  • Wrist placement offers superior comfort and tolerability, making it a preferred option for long-term monitoring.
  • Combining objective actigraphy with subjective self-reports provides a comprehensive evaluation of physical activity in multiple sclerosis.