Related Experiment Video

Updated: Jul 15, 2026

Ultrasound Assessment of Flow-Mediated Dilation of the Brachial and Superficial Femoral Arteries in Rats
09:40

Ultrasound Assessment of Flow-Mediated Dilation of the Brachial and Superficial Femoral Arteries in Rats

Published on: November 3, 2016

Evaluation of haemodynamic flow to the hip in patients with systemic lupus erythematosus

C W Lee1, H J Kim, M J Shin

  • 1Department of Rheumatology, Wallace Memorial Baptist Hospital, Gumjung-gu Namsan-dong 374-75, Busan, Korea. choong@wmbh.co.kr

Scandinavian Journal of Rheumatology
|April 25, 2007
PubMed

Insights

Systemic lupus erythematosus (SLE) patients show higher blood flow in the proximal femur arteries compared to healthy individuals. This study evaluated haemodynamic flow to the femur head in SLE patients, identifying potential markers for osteonecrosis risk.

Area of Science:

  • Rheumatology
  • Vascular Biology
  • Medical Imaging

Background:

  • Systemic lupus erythematosus (SLE) is associated with a high risk of osteonecrosis.
  • Currently, no reliable predictive tests exist to identify osteonecrosis in SLE patients.
  • Understanding vascular changes in the proximal femur is crucial for early detection.

Purpose of the Study:

  • To evaluate the haemodynamic flow characteristics in the proximal femur arteries of SLE patients.
  • To identify potential ultrasound-based markers for assessing osteonecrosis risk in SLE.
  • To compare vascular parameters between SLE patients and healthy controls.

Main Methods:

  • Ultrasound with color and power Doppler was used to examine medial and lateral circumflex arteries.
  • Evaluated 44 hips in 22 SLE patients and 30 hips in 15 healthy controls.
  • Measured peak systolic velocity (PSV) and pulsatility index (PI) in neutral and internal rotation positions.

Main Results:

  • SLE patients exhibited significantly higher PSV compared to healthy controls in both neutral (70.6 vs. 46.9) and internal rotation (74.8 vs. 49.9) positions.
  • PI was also significantly elevated in SLE patients versus controls in neutral (8.9 vs. 5.5) and internal rotation (8.1 vs. 3.9) positions.
  • These differences were statistically significant (p<0.001).

Conclusions:

  • Arterial pulsatility index (PI) and peak systolic velocity (PSV) in the femur head arteries are significantly higher in SLE patients.
  • These findings suggest potential haemodynamic alterations that may be linked to osteonecrosis risk in SLE.
  • Ultrasound assessment of femur head arterial flow could aid in predicting osteonecrosis in SLE patients.
Abstract

More Related Videos

Doppler Ultrasound-Based Leg Blood Flow Assessment During Single-Leg Knee-Extensor Exercise in an Uncontrolled Setting09:18

Doppler Ultrasound-Based Leg Blood Flow Assessment During Single-Leg Knee-Extensor Exercise in an Uncontrolled Setting

Published on: December 15, 2023

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry07:12

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry

Published on: January 19, 2020

Related Concept Videos

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Assessment of the Cardiovascular System III: Palpation01:27

Assessment of the Cardiovascular System III: Palpation

Palpation involves feeling the body to evaluate texture, size, consistency, and tenderness for assessing cardiovascular health. The following steps are organized in a head-to-toe order:
Jugular Venous Pressure (JVP) Measurement
Position the patient at a thirty- to forty-five-degree angle or in a semi-fowler's position. Look for the highest point of pulsation in the internal jugular vein and measure the vertical distance to the angle of Loius or sternal angle. A normal JVP is 3-4 cm above the...
Assessing Blood pressure using a doppler ultrasound01:19

Assessing Blood pressure using a doppler ultrasound

To obtain accurate blood pressure measurements in clinical settings, especially when traditional methods are insufficient, healthcare professionals utilize the Doppler ultrasound technique. This method uses high-frequency sound waves to detect blood flow within the arteries, which is crucial for patients with conditions that complicate circulatory system assessment.
Pre-Procedural Guidelines for Doppler Ultrasound Blood Pressure Assessment:
Preparation of Equipment:
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...