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Real-Time Void Spot Assay
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Published on: February 10, 2023

Bladder dysfunction in type 2 diabetic patients.

Nur Kebapci1, Aydin Yenilmez, Belgin Efe

  • 1Department of Endocrinology and Metabolism, Osmangazi University Medical Faculty, Eskişehir, Turkey. nkebapci@ogu.edu.tr

Neurourology and Urodynamics
|April 25, 2007
PubMed
Summary

Diabetic cystopathy is common in type 2 diabetes, affecting bladder function. Factors like age, diabetes duration, and complications help predict bladder dysfunction in patients.

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Published on: August 9, 2012

Area of Science:

  • Urology
  • Endocrinology
  • Diabetology

Background:

  • Type 2 diabetes mellitus (T2DM) frequently leads to lower urinary tract symptoms (LUTS).
  • Urodynamic investigation is crucial for diagnosing bladder dysfunction (BD) in diabetic patients.
  • Understanding patient characteristics and chronic complications aids in reevaluating BD findings.

Purpose of the Study:

  • To reevaluate urodynamic findings of bladder dysfunction in type 2 diabetic patients.
  • To correlate patient characteristics and chronic diabetic complications with specific urodynamic findings.
  • To identify predictive factors for bladder dysfunction in type 2 diabetes.

Main Methods:

  • Urodynamic investigation was performed on 54 patients (27 male, 27 female) with LUTS.
  • Findings were classified into diabetic cystopathy (DC), detrusor overactivity, bladder outlet obstruction (BOO), or incontinence.
  • Evaluated parameters included HbA1C, retinopathy, nephropathy, and sensorimotor/autonomic neuropathies.

Main Results:

  • Bladder dysfunction (BD) was observed in 74.07% of men and 59.26% of women.
  • Diabetic cystopathy (DC) was the most frequent finding in both genders.
  • Predictive factors for BD included age, diabetes duration, HbA1C levels, QTc prolongation, retinopathy, and microalbuminuria.

Conclusions:

  • Diabetic cystopathy is the predominant urodynamic finding in type 2 diabetic patients.
  • Age, diabetes duration, metabolic control (HbA1C), and specific complications predict BD.
  • Early identification of DC, typically 8-9 years post-T2DM diagnosis, is vital for patient management.