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Published on: September 2, 2009
Microsponge delivery system
Vikrant Chadawar1, Jessy Shaji
1Dept. of Pharmaceutics, Prin. K.M.Kundnani College of Pharmacy, Plot No. 23, Jote Joy Building, Cuffe Parade, Colaba, Mumbai 400 005, India.
Abstract:
Microsponges are polymeric delivery systems consisting of porous microspheres having a size range in between 5 to 300 microm depending upon the degree of smoothness or after feel required for the end formulations. Microsponge Delivery System MDS is a unique technology for controlled delivery of drug. The present review introduces Microsponge technology along with its synthesis, characterization, programmable parameters and release mechanism of MDS. Wide ranges of applications are also suggested to develop drug or cosmetic products with enhanced safety and efficacy. MDS can provide increased efficacy for topically active agents with enhanced safety, extended product stability and improved aesthetic properties in an efficient and novel manner.
Insights
Microsponges are porous polymeric microspheres for controlled drug delivery. This technology enhances topical agent efficacy, safety, and product stability in novel drug and cosmetic formulations.
Area of Science:
- Polymer science
- Materials science
- Pharmaceutical technology
Background:
- Microsponges are polymeric delivery systems composed of porous microspheres.
- These microspheres range from 5 to 300 micrometers in size.
- Microsponge Delivery System (MDS) offers a unique approach to controlled drug delivery.
Purpose of the Study:
- To review Microsponge technology, including its synthesis and characterization.
- To explore the programmable parameters and release mechanisms of MDS.
- To suggest applications for enhanced drug and cosmetic products.
Main Methods:
- Review of existing literature on Microsponge technology.
- Analysis of synthesis and characterization techniques for microsponges.
- Examination of factors influencing drug release from MDS.
Main Results:
- MDS utilizes porous polymeric microspheres for controlled release.
- Key parameters influencing MDS performance include size and formulation.
- The technology allows for tunable drug release profiles.
Conclusions:
- Microsponge Delivery System offers enhanced efficacy and safety for topical agents.
- MDS improves product stability and aesthetic properties.
- This technology presents novel opportunities for drug and cosmetic product development.
