Related Experiment Video
Updated: Jul 15, 2026

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model
Published on: September 4, 2017
Iris cavernous hemangioma associated with multiple cavernous hemangiomas in the kidney, brain, and skin
Archana Thangappan1, Carol L Shields, Marc Dinowitz
1Ocular Oncology Service, Wills Eye Hospital, Thomas Jefferson University, Philadelphia, PA, USA.
Purpose:
To document the relationship of iris cavernous hemangiomas with multiorgan hemangiomas in a child.
Methods:
A 7-year-old girl with kidney hemangiomas, brain hemangiomas, and skin hemangiomas developed blurred vision and darkening of the right iris. She had undergone 6 previous brain surgeries and multiple revisions of a ventriculoperitoneal shunt for hydrocephalus beginning at age 3 months.
Results:
Examination revealed visual acuity of 20/30 in the right eye and 20/20 in the left eye. There was a reddish-purple lobulated cystic mass along the superior iris pupillary margin measuring 2 mm in greatest diameter confirmed by ultrasound biomicroscopy. The remainder of the ocular examination was unremarkable. The diagnosis was iris cavernous hemangioma in a patient with multiorgan cavernous hemangiomatosis. By 1-year follow-up, the iris hemangioma deflated, leaving a fibrotic, involuted scar.
Conclusions:
Iris cavernous hemangioma can be associated with multiorgan hemangiomas that can be life threatening.
Related Concept Videos
Cerebral Edema ll: Pathophysiology
Blood and Nerve Supply to the Kidney
Bloody Supply to the Kidneys:
The kidneys receive their blood supply from the renal arteries, which branch off from the abdominal aorta—the main artery supplying the abdomen and lower body. The renal arteries enter the kidneys at the hilum, a notch on the medial side of each...
Cirrhosis I: Introduction
Renal Corpuscle
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous capillaries...
Portal Hypertension
Hemorrhagic Stroke l: Introduction

