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Updated: Jul 15, 2026
06:08
Establishment and Characterization of Patient-Derived Xenograft Models of Anaplastic Thyroid Carcinoma and Head and Neck Squamous Cell Carcinoma
Published on: June 2, 2023
Aggressive primary thyroid non Hodgkin's lymphoma with pregnancy
Khaled B Soliman1, Mohamed M Abbas, Mahmoud A Seksaka
1Department of Obstetrics and Gynecology, Maternity and Children Hospital, Buraidah, Qassim, Kingdom of Saudi Arabia. khaled_b_s@yahoo.com
Saudi Medical Journal
|April 26, 2007
Summary
A pregnant patient with aggressive thyroid non-Hodgkin lymphoma experienced severe respiratory distress. Treatment with chemotherapy led to a dramatic response, enabling a safe delivery at 36 weeks gestation.
Area of Science:
- Oncology
- Obstetrics and Gynecology
- Hematology
Background:
- Thyroid cancer during pregnancy is rare.
- Aggressive non-Hodgkin lymphoma can present with significant compressive symptoms.
Observation:
- A multigravida patient at 30 weeks gestation presented with a large neck mass, severe respiratory distress, dysphagia, and hoarseness.
- Diagnosis revealed aggressive non-Hodgkin lymphoma of the thyroid gland.
Findings:
- The patient received 6 cycles of chemotherapy.
- A dramatic response was observed after the first cycle.
- Successful, elective labor was induced at 36 weeks gestation with favorable outcomes for mother and child.
Implications:
- This case highlights the successful management of aggressive thyroid lymphoma in pregnancy.
- Multidisciplinary care involving oncology, hematology, and obstetrics is crucial.
- Chemotherapy can be safely administered during the third trimester with favorable outcomes.
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