Autogenous bone and platelet-rich plasma (PRP) in the treatment of intrabony defects

Obtaining an answer to the question whether autogenous bone in combination with PRP give a therapeutical effect in the form of periodontal ligament attachment regeneration. Defining the degree of elimination of a convenient environment for subgingival bacterial plaque by reduction of periodontal pocket depth and periodontitis.

Twenty-six systematically healthy patients with diagnosed chronic and advanced periodontitis (24 females and 2 males) were selected for the study. In general 72 periodontal infrabony pockets were treated. Clinically the following indexes were examined and measured: 1. Plaque Index by Silness and Löe. 2. Sulcus Bleeding Index by Mühlemann and Son. 3. Clinical Attachment Level (mm). 4. Pocket Depth (mm). 5. Gingival Recession (mm). 6. Tooth mobility with the use of Periotest. 7. Degree of alveolar bone loss with the use of Engelberger, Marthaler and Rateitschak index - EMR Index.

At 12 months after treatment the following results were noted: Mean value of attachment level regeneration 3.47 mm. Mean value of pocket depth decreased by 3.7 mm. Mean value of tooth mobility reduction by 48.3%. Megeneration of alveolar bone by 9.24%.

1. Autogenous bone with added PRP in treatment of intrabony defects caused by periodontitis have given significant clinical improvement of the periodontal tissues. 2. The combination of PRP and autogenous bone caused the elimination of a convenient environment for subgingival bacterial plaque eliminating periodontitis.