Related Experiment Video
Updated: Jul 15, 2026
07:52
Detection of Antibodies That Neutralize the Cellular Uptake of Enzyme Replacement Therapies with a Cell-based Assay
Published on: September 10, 2018
Drug evaluation: zanolimumab, a human monoclonal antibody targeted against CD4
1Skin Cancer Center Charité, Department of Dermatology, Venereology and Allergy, Charité-Universitätsmedizin Berlin, Fabeckstr 60-62, 14195 Berlin, Germany. chalid.assaf@charite.de
Current Opinion in Molecular Therapeutics
|April 27, 2007
Abstract:
Merck Serono SA, under license from Genmab A/S and Medarex Inc, is developing zanolimumab, a human mAb targeted against CD4, for the potential treatment of cutaneous (CTCL) and noncutaneous (NCTCL) T-cell lymphomas. Zanolimumab is currently undergoing phase III clinical trials for CTCL and phase II clinical trials for NCTCL.
