Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jul 15, 2026

Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation
09:32

Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation

Published on: September 19, 2018

Development of a computer model to predict aortic rupture due to impact loading.

C S Shah1, K H Yang, W Hardy

  • 1Bioengineering Center, Wayne State University, Detroit, MI.

Stapp Car Crash Journal
|April 27, 2007
PubMed
Summary

Developing a computer model to predict aortic rupture from blunt chest impacts is crucial. This model simulates blood flow and pressure, identifying right-sided impacts as most hazardous for potential aortic isthmus rupture.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Epidemiology, prevention and control of cervical cancer in middle-aged and elderly women in China].

Zhonghua zhong liu za zhi [Chinese journal of oncology]·2025
Same author

[Clinical analysis of 8 cases of spontaneous cerebrospinal fluid rhinorrhea with aspiration pneumonia].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery·2024
Same author

Species of <i>Botryosphaeriaceae</i> associated with citrus branch diseases in China.

Persoonia·2023
Same author

[Development of a Ranking Tool for Scientificity, Transparency and Applicability of Clinical Practice Guidelines].

Zhonghua yi xue za zhi·2022
Same author

Enhanced charge density wave coherence in a light-quenched, high-temperature superconductor.

Science (New York, N.Y.)·2022
Same author

Lower Extremity Impact and Injury Responses of Male and Female PMHS to High-Rate Vertical Loading.

Annals of biomedical engineering·2021

Area of Science:

  • Biomechanics
  • Computational modeling
  • Trauma research

Background:

  • Blunt thoracic impacts can cause fatal aortic rupture.
  • Cadaver testing is expensive, time-consuming, and often unsuccessful for studying aortic rupture mechanisms.
  • Previous finite element models of the thorax lacked detailed aortic fluid dynamics.

Purpose of the Study:

  • To develop and validate a computational model predicting aortic rupture modes.
  • To identify loading conditions most likely to cause aortic rupture.
  • To enhance understanding of factors influencing aortic injury in blunt trauma.

Main Methods:

  • Developed a 3D finite element model of the human thorax, incorporating fluid elements for blood.
  • Included detailed anatomical structures: heart, lungs, rib cage, spine, diaphragm, major vessels.

Related Experiment Videos

Last Updated: Jul 15, 2026

Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation
09:32

Manufacturing Abdominal Aorta Hydrogel Tissue-Mimicking Phantoms for Ultrasound Elastography Validation

Published on: September 19, 2018

  • Validated the model globally against experimental data from frontal and lateral pendulum impact tests.
  • Main Results:

    • Simulations indicated ligamentum arteriosum, subclavian artery, parietal pleura, and intra-aortic pressure changes influence rupture.
    • Right-sided chest impacts were predicted as potentially more hazardous than other directions.
    • The aortic isthmus was identified as the most probable site for aortic rupture, irrespective of impact direction.

    Conclusions:

    • The validated computational model provides insights into aortic rupture mechanisms.
    • Right-sided impacts and specific anatomical factors increase the risk of aortic rupture.
    • Further local-level validation requires experimental data to refine the model for predicting specific aortic injuries.