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Updated: Jul 15, 2026

Formation of Ordered Biomolecular Structures by the Self-assembly of Short Peptides
Published on: November 21, 2013
Self-assembly of conjugated polymers and ds-oligonucleotides directed fractal-like aggregates
Haiyang Gan1, Yuliang Li, Huibiao Liu
1Beijing National Laboratory for Molecular Sciences (BNLMS), CAS Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100080, People's Republic of China.
Abstract:
Highly ordered nanostructures between conjugated polymers and ds-oligonucleotides have been first fabricated by simply controlling the self-assembly processes, which shows a novel concept for fabricating fractal-like structures. The formation of polymer/DNA fractal-like aggregates is a diffusion-limited aggregation (DLA) process. The fractal dimension is independent of the polymer/DNA concentration but only related to the polymer/DNA charge ratio. More interestingly, the different fluorescent resonance energy transfer (FRET) behavior between the polymer and the DNA can be used to distinguish dsDNA from ssDNA.
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