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Updated: Jul 15, 2026

Anti-Nuclear Antibody Screening Using HEp-2 Cells
Published on: June 23, 2014
Psoriasis and hepatitis C treated with anti-TNF alpha therapy (etanercept)
Roberto Cecchi1, Laura Bartoli
1Department of Dermatology, Spedali Riuniti, V. Matteotti 1, 51100 Pistoia, Italy. r.cecchi@usl3.toscana.it
Abstract:
The treatment of severe psoriasis in patients with concomitant hepatitis-C virus infection is quite difficult because several systemic anti-psoriatic drugs are contraindicated owing to their liver toxicity. Recent observations in the literature suggest that etanercept is an effective and safe therapy for this setting of patients. We present a 45-year-old man with extensive plaque psoriasis and concurrent hepatitis C, successfully treated with 12-month etanercept monotherapy. Regular controls of hepatic enzymes and viral load during the treatment disclosed no worsening of baseline values. This case confirms that etanercept may be a safe option for the therapy of patients with psoriasis and hepatitis-C virus infection.
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