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Cross-talk between aging and cancer: the epigenetic language

Mario F Fraga1, Ruben Agrelo, Manel Esteller

  • 1Epigenetics Laboratory, Spanish National Cancer Centre (CNIO), 28029 Madrid, Spain. mffraga@cnio.es

Annals of the New York Academy of Sciences
|April 27, 2007
PubMed
Summary

Cancer risk rises with age due to accumulated molecular lesions in progenitor cells. Epigenetic alterations, like DNA methylation changes, play a key role in aging and cancer development.

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