Penile metastasis from a T1b prostate carcinoma

Area of Science:

• Oncology
• Urology

Background:

• Incidental prostate carcinoma, particularly penile metastasis, is an undocumented phenomenon.
• This report details a unique case of a 72-year-old male with incidental prostate adenocarcinoma.

Observation:

• The patient underwent prostate surgery for benign prostatic obstruction, revealing incidental prostate adenocarcinoma.
• Despite initial negative biopsies, rising prostate-specific antigen (PSA) levels necessitated radiotherapy and hormonal therapy.
• Four years post-surgery, the patient developed a painful penile nodule, confirmed as prostate adenocarcinoma metastasis.

Findings:

• The patient underwent partial penectomy and subsequent medical therapy for disease progression.
• Despite treatment, the patient experienced disease progression and passed away 20 months after diagnosis of penile metastasis.
• Throughout the illness, prostate-specific antigen (PSA) and testosterone levels remained consistently low.

Implications:

• This case underscores the uncertainty surrounding the biological behavior of incidentally detected prostate cancer.
• It highlights the critical need for optimal management strategies and questions the adequacy of current treatment recommendations for such cases.