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Interferon-related leukoencephalopathy in a patient with renal cell carcinoma
O Merimsky1, I Reider, E Merimsky
1Department of Oncology, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, Israel.
Tumori
|August 31, 1991
Abstract:
A 75-year-old patient with metastatic renal cell carcinoma was treated with recombinant interferon alpha-C and thereafter developed a neurologic syndrome of dementia, ataxia, confusional state, loss of concentration ability and cortical blindness. CT scan findings were compatible with leukoencephalopathy, which is reported as being a toxic effect of interferon.