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Published on: January 15, 2022
Ultrasound attenuated coronary plaque as a risk factor for slow flow or no-reflow during percutaneous coronary
Shinichi Furuichi1, Akira Itoh, Hatsue Ishibashi-Ueda
1Department of Cardiology, Osaka City General Hospital, Miyakojima-hondori, Miyakojima-ku, Osaka.
Insights
Ultrasound-attenuated plaque during percutaneous coronary intervention (PCI) can predict no-reflow complications. This lipid-rich plaque may cause distal embolization, necessitating protective devices during PCI.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
- Medical Imaging
Background:
- Slow flow or no-reflow is a significant complication during percutaneous coronary intervention (PCI).
- Risk factors for no-reflow during PCI remain incompletely understood.
- Stable angina necessitates coronary angiography and intervention.
Observation:
- Intravascular ultrasound revealed an ultrasound-attenuated coronary plaque characterized by eccentricity and reduced echo backscatter.
- The plaque lacked calcification but was bulky and eccentric in the left anterior descending artery.
- Directional coronary atherectomy (DCA) was performed due to the lesion's characteristics.
Findings:
- Serious no-reflow occurred immediately after DCA.
- Analysis of the DCA specimen indicated lipid-laden atheromatous gruel.
- This gruel likely attenuated ultrasound reflection and caused distal embolization, leading to no-reflow.
Implications:
- Ultrasound-attenuated coronary plaque is identified as a predictor of no-reflow during PCI.
- The findings suggest a need for enhanced distal protection strategies during interventions involving such plaques.
- Further research into plaque characteristics and their association with PCI complications is warranted.
Abstract:
Slow flow or no-reflow is a serious complication during percutaneous coronary intervention (PCI), but little is known about the risk factors. A 64-year-old man underwent coronary angiography and PCI for stable angina. Pre-interventional intravascular ultrasound demonstrated an ultrasound attenuated coronary plaque, as a long eccentric bulky plaque with a marked decrease of the back echo without calcification. Since the lesion was highly eccentric in the large left anterior descending artery, directional coronary atherectomy (DCA) and subsequent stent implantation were planned. Serious no-reflow occurred after DCA. The DCA specimen suggested that the lipid-laden atheromatous gruel could attenuate the ultrasound reflection and cause distal embolization, resulting in no-reflow during PCI. The presence of ultrasound attenuated coronary plaque is a predictor of slow flow or no-reflow in PCI, indicating that distal protection devices may be required during the procedure.
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