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Common carotid arterial thrombosis associated with ulcerative colitis
Hitoshi Nogami1, Tsuneo Iiai, Satoshi Maruyama
1Division of Digestive and General Surgery, Department of Surgery, Niigata University, School of Medicine, Asahimachidouri1-757 Niigata, 951-8510, Japan. h-nogami@med.niigata-u.ac.jp
World Journal of Gastroenterology
|April 28, 2007
Summary
A rare case of ulcerative colitis (UC) complicated by carotid artery thrombosis is presented. Antithrombotic therapy for stroke may worsen bowel disease, highlighting a complex treatment challenge.
Area of Science:
- Neurology and Gastroenterology
- Vascular Medicine
- Inflammatory Bowel Disease Research
Background:
- Ulcerative colitis (UC) is a chronic inflammatory bowel disease.
- Cerebral infarction and arterial thrombosis are rare but serious complications.
Observation:
- A 26-year-old woman with UC presented with left hemiparesis due to cerebral infarction.
- Imaging revealed thrombosis in the right common and internal carotid arteries.
- Antithrombotic and anticoagulant therapies were initiated for the cerebral event.
Findings:
- The patient experienced increased diarrhea frequency during antithrombotic treatment.
- Emergency subtotal colectomy was performed, followed by rectal hemorrhage and further resection.
- Neurological status and vascular imaging showed no improvement despite continued anticoagulation.
Implications:
- This case highlights a rare complication of UC: common carotid arterial thrombosis.
- Antithrombotic and anticoagulant therapies may exacerbate underlying bowel disease in UC patients.
- Careful consideration of treatment strategies is crucial in managing complex UC cases with vascular complications.
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