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Updated: Jul 15, 2026

Cell-free Biochemical Fluorometric Enzymatic Assay for High-throughput Measurement of Lipid Peroxidation in High Density Lipoprotein
Published on: October 12, 2017
Variability in apo(a) gene regulatory sequences, compound genotypes, and association with Lp(a) plasma levels
Katerina Zídková1, Lukás Zlatohlávek, Richard Ceska
13rd Medical Department, 1st Faculty of Medicine and General Teaching Hospital, Charles University, Prague, Czech Republic. kzidk@lfl.cuni.cz
Objectives:
Lipoprotein(a) is an independent risk factor of atherosclerosis.
Design And Methods:
We assigned frequencies of six polymorphic sites from apo(a) gene transcription control regions, linkage disequilibrium, and 5-polymorphic compound genotypes association with Lp(a) levels.
Results:
Significant linkage disequilibrium between polymorphic sites was detected. Compound genotypes were significantly associated with Lp(a) levels (P<0.0001). Major 5-polymorphic genotypes were distributed in a broad range of concentrations.
Conclusions:
Major 5-polymorphic compound genotypes are not associated with restricted range of Lp(a) levels.
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