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Updated: Jul 15, 2026

Turbidimetry on Human Washed Platelets: The Effect of the Pannexin1-inhibitor Brilliant Blue FCF on Collagen-induced Aggregation
Published on: April 6, 2017
[218 tooth extraction in patients taking platelet aggregation inhibitors]
J Garnier1, F Truchot, J Quero
1Département d'odontologie et de chirurgie buccale, faculté d'odontologie, université de Rennes-I, CHU de Rennes, 2, avenue du Professeur-Léon-Bernard, bâtiment 15, 35043 Rennes cedex, France.
Tooth extraction is safe for patients on antiplatelet agents. Applying local hemostasis protocols effectively manages bleeding risk, minimizing complications during dental procedures.
Area of Science:
- Oral surgery
- Cardiology
- Pharmacology
Context:
- Patients on antiplatelet agents require careful management for dental procedures.
- Antiplatelet therapy is crucial for preventing thrombotic diseases.
Purpose:
- To evaluate the safety and hemostatic control of tooth extraction in patients undergoing antiplatelet therapy.
- To determine the incidence of bleeding complications in this patient group.
Summary:
- A retrospective analysis of 52 patients (218 extractions) on antiplatelet agents was conducted.
- A local hemostasis protocol (filling, suture, compression) was applied to all extractions.
- A low rate of hemorrhagic complications (1.3% sockets, 1.9% patients) was observed, with bleeding effectively managed by local hemostasis.
Impact:
- Demonstrates that tooth extractions can be safely performed in patients on antiplatelet therapy.
- Highlights the efficacy of local hemostasis in controlling post-extraction bleeding.
- Supports the continuation of antiplatelet therapy during necessary dental extractions.
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