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Published on: October 29, 2014
The epidemiology of bacterial meningitis
A D Walling1, K J Kallail, D Phillips
1Department of Family and Community Medicine, University of Kansas School of Medicine-Wichita 67214-3199.
Background:
The incidence by age and causative organism of bacterial meningitis are not known on a community basis.
Methods:
The epidemiology of bacterial meningitis in a metropolitan county was studied by identifying all cases admitted to a hospital from 1983 through 1987.
Results:
The overall incidence of bacterial meningitis was 5 per 100,000 person-years, but numbers of cases ranged from 40 per 100,000 for children younger than 5 years to 1.0 per 100,000 in adults aged between 16 and 64 years. No significant excesses of cases were found in male patients or in blacks. The predominant causative organism varied with age. Overall, Haemophilus influenzae was the most common causative organism, but 32 percent of cases were due to Streptococcus pneumoniae. Case fatality rates were high for S. pneumoniae (12.5 percent) and very high for the small number of elderly patients suffering from bacterial meningitis.
Conclusions:
Significant declines have occurred in the last decade in the incidence of bacterial meningitis in children, particularly in those younger than 5 years, and in disease caused by H. influenzae and group B streptococcus.
Insights
Bacterial meningitis incidence varies by age, with children under 5 most affected. Significant declines in childhood bacterial meningitis and Haemophilus influenzae cases have been observed.
Area of Science:
- Epidemiology
- Infectious Diseases
- Public Health
Background:
- Community-level incidence and causative organisms of bacterial meningitis were previously unknown.
- Understanding age-specific risks and common pathogens is crucial for public health interventions.
Purpose of the Study:
- To determine the community-based incidence and age distribution of bacterial meningitis.
- To identify the predominant causative organisms and their age-related patterns.
- To assess case fatality rates associated with different pathogens and age groups.
Main Methods:
- A retrospective epidemiological study of bacterial meningitis cases admitted to hospitals in a metropolitan county.
- Data collection spanned from 1983 to 1987, covering a five-year period.
- Analysis included incidence rates by age, causative organism identification, and case fatality rates.
Main Results:
- Overall bacterial meningitis incidence was 5 per 100,000 person-years.
- Children under 5 years had the highest incidence (40 per 100,000), while adults aged 16-64 had the lowest (1.0 per 100,000).
- Haemophilus influenzae was the most common organism overall, followed by Streptococcus pneumoniae (32%). Case fatality rates were high for S. pneumoniae (12.5%) and elderly patients.
Conclusions:
- Bacterial meningitis incidence has significantly decreased in the last decade, especially in children under 5.
- Reductions were particularly noted for diseases caused by Haemophilus influenzae and group B Streptococcus.
- Ongoing surveillance is essential to monitor trends and guide prevention strategies.
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