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Results from international questionnaires.

Zaccaria Ricci1, Sergio Picardo, Claudio Ronco

  • 1Department of Pediatric Cardiology and Cardiac Surgery, Bambino Gesù Hospital, Rome, Italy. z.ricci@libero.it

Contributions to Nephrology
|April 28, 2007
PubMed
Summary
This summary is machine-generated.

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Renal replacement therapy (RRT) shows global variability in acute kidney injury treatment, particularly in dialysis mode and dose. While continuous RRT is common, achieving adequate dialysis dose remains a challenge for many centers worldwide.

Area of Science:

  • Nephrology and Critical Care Medicine
  • Epidemiology of Renal Replacement Therapy

Background:

  • Renal replacement therapy (RRT) standards vary globally, especially in acute kidney injury (AKI) management.
  • Significant disparities exist in dialysis prescription and delivery across different healthcare centers.

Purpose of the Study:

  • To review the global epidemiology of dialysis prescription and delivery.
  • To identify trends and challenges in RRT practices worldwide.

Main Methods:

  • Analysis of recent observational studies and international surveys on RRT practices.
  • Examination of dialysis prescription patterns and delivery in various healthcare settings.

Main Results:

  • Continuous RRT is utilized in 80% of intensive care units globally.

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  • Despite consensus on adequate clearance (35 ml/kg/h), few patients receive it; however, prescribing adequate doses is increasing.
  • Many centers lack specific adequacy targets and fail to measure effective delivery, facing barriers like cost and logistics.

    • Conclusions:

    • Surveys indicate a trend towards continuous therapies and higher RRT dosage over the past decade.
    • Further high-quality scientific evidence is needed to guide definitive RRT indications and prescriptions.