Related Experiment Video
Updated: Jul 15, 2026

Inducing Meningococcal Meningitis Serogroup C in Mice via Intracisternal Delivery
Published on: November 5, 2019
Streptococcal meningitis following myelogram procedures
Jennifer Hsu1, Bette Jensen, Matthew Arduino
1Division of Healthcare Quality Promotion, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
Abstract:
In September of 2004, we investigated 7 cases of post-myelography meningitis. Streptococcal species were recovered from blood or cerebrospinal fluid in all cases. Our findings suggest that droplet transmission of the oral flora of the clinician performing the procedure was the most likely source of these infections. The Centers for Disease Control and Prevention recommends the use of face masks by those performing myelograms.
Insights
Post-myelography meningitis cases were linked to streptococcal infections. Droplet transmission from clinicians performing the procedure is the likely source, highlighting the need for face masks.
Area of Science:
- Infectious Diseases
- Neurology
- Public Health
Background:
- Meningitis following myelography is a rare but serious complication.
- Previous studies have explored potential causes of post-procedural infections.
Purpose of the Study:
- To investigate the source and causative agents of seven cases of meningitis occurring after myelography in September 2004.
- To identify transmission routes and recommend preventive measures.
Main Methods:
- Case series investigation of seven patients with post-myelography meningitis.
- Microbiological analysis of blood and cerebrospinal fluid (CSF) samples.
- Epidemiological investigation to determine the source of infection.
Main Results:
- Streptococcal species were identified in blood or CSF samples from all seven patients.
- Droplet transmission of oral flora from the performing clinician was identified as the most probable source.
- The infections were linked to the myelography procedure.
Conclusions:
- Clinician-to-patient droplet transmission is a significant risk factor for post-myelography meningitis.
- The Centers for Disease Control and Prevention (CDC) recommends face mask usage during myelography to prevent such infections.
Related Concept Videos
Bacterial Meningitis I: Introduction
Bacterial Meningitis
Bacterial Meningitis II: Pathophysiology
Viral Meningitis
Streptococcal Pharyngitis
Cryptococcal Meningitis
