Related Experiment Video
Updated: Jul 15, 2026

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
Published on: April 5, 2024
Simultaneous ovarian and endometrial osseous metaplasia: a case report
Sebastiano Campo1, Vincenzo Campo, Gian Franco Zannoni
1Department of Obstetrics and Gynecology, Division of Anatomic Pathology and Histology, Università Cattolica del Sacro Cuore, Rome, Italy. scampo@rm.unicatt.it
Background:
Endometrial ossification is a rare disease. More than 80% of cases occur after pregnancy, but it has been observed in patients with a history of endometritis, dilation and curettage, and metabolic disorders.
Case:
A 42-year-old woman presented with osseous metaplasia of both the endometrium and ovaries. At laparoscopy both adnexa were covered with adhesions and were adherent to the posterior wall of the uterus. Following adhesiolysis, calcified nodules were removed from both ovaries with biopsy forceps. Endometrial bone tissue was removed by hysteroscopic resection.
Conclusion:
To our knowledge, this is the first reported case of osseous metaplasia of both the endometrium and ovaries since all cases described to date in the literature involved only the uterine cavity. Conservative management with endoscopic surgery is effective.

