Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fractures: Bone Repair01:27

Fractures: Bone Repair

Treatment for a fracture is based on the type of break, the bone affected, and the patient's age.
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Discovery of TCR-like antibodies to the KRAS G12D neoantigen via in silico-in vitro workflow.

Molecular therapy : the journal of the American Society of Gene Therapy·2026
Same author

Bi-allelic WDHD1 variants cause microcephalic primordial dwarfism.

American journal of human genetics·2026
Same author

Noninvasive Nicotine Quantitation and Flavor Differentiation of <i>on!</i> Nicotine Pouches Using Raman Spectroscopy: A Direct, Reliable, and Preparation-Free Approach.

ACS omega·2026
Same author

Epigenome-wide analysis identifies DNA methylation mediators of treatment-related cardiometabolic risk in survivors of childhood cancer.

Nature communications·2026
Same author

Fine-tuning signal strength in CD5 CAR-NK cells for targeted T cell cancer therapy.

Frontiers in immunology·2025
Same author

Designing Hand and Forearm Gestures to Control Virtual Forearm for User-Initiated Forearm Deformation.

IEEE transactions on visualization and computer graphics·2025

Related Experiment Video

Updated: Jul 15, 2026

Treatment of Facial Deformities using 3D Planning and Printing of Patient-Specific Implants
07:11

Treatment of Facial Deformities using 3D Planning and Printing of Patient-Specific Implants

Published on: May 23, 2020

Early correction of a developing skeletal Class III malocclusion.

Zuisei Kanno1, Yoonji Kim, Kunimichi Soma

  • 1Orthodontic Science, Department of Orofacial Development and Function, Division of Oral Health Science, Tokyo Medical and Dental University, Yushima, Tokyo, Japan. z.kanno.orts@tmd.ac.jp

The Angle Orthodontist
|May 1, 2007
PubMed
Summary

This case report details successful orthodontic treatment for a severe Class III malocclusion in a young Japanese girl. The combined approach significantly improved facial aesthetics and bite alignment, with stable results.

More Related Videos

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

Related Experiment Videos

Last Updated: Jul 15, 2026

Treatment of Facial Deformities using 3D Planning and Printing of Patient-Specific Implants
07:11

Treatment of Facial Deformities using 3D Planning and Printing of Patient-Specific Implants

Published on: May 23, 2020

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible
10:42

A Postoperative Evaluation Guideline for Computer-Assisted Reconstruction of the Mandible

Published on: January 28, 2020

Area of Science:

  • Orthodontics and Dentofacial Orthopedics
  • Pediatric Dentistry

Background:

  • Severe Class III malocclusion characterized by a concave profile, hypodivergent skeletal pattern, anterior crossbite, and deep overbite.
  • Facial asymmetry due to a lateral mandibular shift to avoid incisal interferences.

Observation:

  • An 11-year-old Japanese girl presented with a complex malocclusion and facial asymmetry.
  • Treatment involved a monoblock appliance, rapid palatal expansion, and fixed edgewise appliances.

Findings:

  • The monoblock appliance facilitated clockwise mandibular growth redirection and corrected incisal relationships.
  • Significant improvements in facial esthetics and occlusion were achieved within 28 months.
  • Excellent stability of the treatment outcome was confirmed at an 18-year-old follow-up.

Implications:

  • This treatment approach offers a viable solution for correcting severe Class III malocclusion in growing patients.
  • Early intervention can lead to substantial improvements in both function and facial harmony.
  • The described multi-stage treatment strategy demonstrates long-term stability and efficacy.