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Updated: Jul 15, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Analysis of ¹⁸FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Tuberculous Addison's disease: morphological and quantitative evaluation with multidetector-row CT.

En-Sen Ma¹, Zhi-Gang Yang, Yuan Li

¹Department of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China.

European Journal of Radiology

|May 1, 2007

Summary

Multidetector-row computed tomography (MDCT) reveals characteristic adrenal gland changes in tuberculous Addison's disease. This imaging modality aids in diagnosing and staging adrenal tuberculosis with high accuracy when combined with clinical data.

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Last Updated: Jul 15, 2026

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Analysis of ¹⁸FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Area of Science:

Radiology
Medical Imaging
Endocrinology

Background:

Tuberculous Addison's disease is a significant cause of adrenal insufficiency.
Accurate diagnosis and staging are crucial for effective management.

Purpose of the Study:

To characterize tuberculous Addison's disease using multidetector-row computed tomography (MDCT).
To evaluate the utility of MDCT in diagnosing and staging adrenal tuberculosis.

Main Methods:

Retrospective analysis of unenhanced and contrast-enhanced MDCT scans in 19 patients.
Assessment of adrenal gland features including size, contour, calcification, and enhancement patterns.
Correlation of disease duration with calcification incidence.

Main Results:

Bilateral adrenal involvement was universal (100%).
Gland enlargement (94.7%) or atrophy (5.3%) was observed.
Calcification occurred in 42.1% of glands, increasing with disease progression.
Mass-like changes and heterogeneous enhancement were common in enlarged glands.

Conclusions:

MDCT effectively demonstrates the characteristic morphology and CT attenuation of tuberculous Addison's disease.
MDCT, combined with clinical and biochemical findings, offers high specificity and accuracy for diagnosing and staging adrenal tuberculosis.