Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Inflated, dried whole lung specimens.

M J Oldham1, R F Phalen

  • 1Community and Environmental Medicine, University of California, Irvine 92717.

The Anatomical Record
|October 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Fit-for-purpose characterization of air-liquid-interface (ALI) in vitro exposure systems for e-vapor aerosol.

Toxicology in vitro : an international journal published in association with BIBRA·2022
Same author

Variability of TSNA in U.S. Tobacco and Moist Smokeless Tobacco Products.

Toxicology reports·2020
Same author

Preface.

Inhalation toxicology·2015
Same author

Dosimetry counts: molecular hypersensitivity may not drive pulmonary hyperresponsiveness.

Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine·2007
Same author

Effect of cigarette smoking on nitric oxide, structural, and mechanical properties of mouse arteries.

American journal of physiology. Heart and circulatory physiology·2006
Same author

Methods for modeling particle deposition as a function of age.

Respiration physiology·2001

This study presents a method for preparing fully-inflated whole lung specimens for research and instruction. The technique involves extensive rinsing and air inflation to create permanent, light-colored lung specimens.

Area of Science:

  • Anatomical pathology
  • Medical education

Background:

  • Preserving anatomical specimens is crucial for medical education and research.
  • Existing methods may not consistently yield well-inflated and durable specimens.

Purpose of the Study:

  • To describe a novel method for preparing fully-inflated whole lung specimens.
  • To ensure specimens are suitable for long-term instruction and research.

Main Methods:

  • Lungs are removed, cannulated, and lavaged with tap water over 250 times to remove blood.
  • Specimens are inflated with dehumidified air to 30 cm H2O and dried under pressure.
  • Optional alcohol filling can be performed.

Main Results:

  • The method produces light-colored, fully-inflated whole lung specimens.

Related Experiment Videos

  • The resulting specimens are durable and suitable for permanent storage.
  • The technique ensures structural integrity for educational and research applications.
  • Conclusions:

    • This method provides a reliable way to prepare high-quality lung specimens.
    • The preserved lungs are valuable resources for anatomical study and scientific investigation.