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Pediatric keratoprosthesis.

James V Aquavella1, Matthew D Gearinger, Esen K Akpek

  • 1University of Rochester Eye Institute, Rochester, New York 14642, USA. James_Aquavella@URMC.rochester.edu

Ophthalmology
|May 1, 2007
PubMed
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Boston keratoprosthesis effectively treats pediatric corneal opacity, maintaining a clear visual axis and good outcomes. The device shows excellent retention and is suitable for complex pediatric cases.

Area of Science:

  • Ophthalmology
  • Biomedical Engineering

Background:

  • Pediatric corneal opacity presents a significant challenge in vision restoration.
  • Previous keratoplasty procedures may fail, necessitating alternative treatments.
  • Congenital corneal diseases often lead to severe visual impairment in children.

Purpose of the Study:

  • To evaluate the efficacy and safety of keratoprosthesis implantation for pediatric corneal opacity.
  • To describe the authors' experience with different keratoprosthesis devices in children.
  • To assess outcomes including visual acuity, prosthesis retention, and complications.

Main Methods:

  • A retrospective review of 17 children (22 eyes) with corneal opacification.
  • Patients underwent keratoprosthesis surgery, including AlphaCor and Boston keratoprosthesis devices.

Related Experiment Videos

  • Outcomes measured included intraocular pressure, inflammation, visual axis clarity, visual acuity, and prosthesis retention.

    • Main Results:

    • The Boston keratoprosthesis demonstrated 100% retention without dislocation or extrusion in 21 eyes.
    • A clear visual axis was achieved in all cases, with visual acuity ranging from light perception to 20/30 in older children.
    • Intraocular pressure was controlled, and no cases of surface infection or endophthalmitis were reported.

    Conclusions:

    • The Boston keratoprosthesis is a suitable and effective device for managing pediatric corneal opacity.
    • It rapidly establishes and maintains a clear optical pathway, facilitating vision restoration.
    • The device does not impede the management of concurrent glaucoma or retinopathy.