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Related Experiment Video

Updated: Jul 15, 2026

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle

Published on: January 19, 2017

[The metabolic syndrome exists].

C D A Stehouwer¹

¹Academisch Ziekenhuis Maastricht, afd. Interne Geneeskunde, AZ Maastricht. csteh@sint.azm.nl

Nederlands Tijdschrift Voor Geneeskunde

|May 2, 2007

Summary

The existence of the metabolic syndrome is confirmed by the clustering of cardiovascular risk factors, despite uncertainties regarding its pathophysiology and definition. This clustering, not a specific disease mechanism, defines the syndrome.

Area of Science:

Cardiology
Metabolic Disorders
Public Health

Background:

The metabolic syndrome is a controversial concept with debated pathophysiology and clinical utility.
Cardiovascular risk factors are known to frequently co-occur in individuals.

Purpose of the Study:

To address the ongoing debate surrounding the existence and definition of the metabolic syndrome.
To clarify the basis for the recognition of the metabolic syndrome in clinical practice.

Main Methods:

Review of existing literature and clinical observations regarding cardiovascular risk factors.
Analysis of the definition and diagnostic criteria for the metabolic syndrome.

Main Results:

While the precise pathophysiology and definition remain debated, the clustering of specific cardiovascular risk factors is an undeniable phenomenon.

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Published on: September 27, 2024

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Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle

Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle

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Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome

Pulse-Wave Velocity, Flow-Mediated Dilation, and Carotid Intima-Media Thickness to Assess Cardiovascular Risk in Population with Metabolic Syndrome

Published on: September 27, 2024

This observed clustering is the defining characteristic of the metabolic syndrome.

Conclusions:

The metabolic syndrome exists as a recognized pattern of clustered cardiovascular risk factors.
Further research into pathophysiology is warranted, but the clinical observation of clustering supports the syndrome's existence.