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Updated: Oct 3, 2026

Oral Biofilm Analysis of Palatal Expanders by Fluorescence In-Situ Hybridization and Confocal Laser Scanning Microscopy
Published on: October 20, 2011
[Short-term fluoride release from conseal F fissure sealant in some media--an in vitro study]
Piotr Kosior1, Urszula Kaczmarek
1Zaklad Propedeutyki Stomatologicznej Akademii Medycznej we Wrocławiu
Introduction:
Low fluoride concentrations constantly maintained in the oral cavity are important for caries prevention. Application of fissure sealants containing fluoride improves protection and reinforces caries prophylaxis. The aim of this study was to assess the level of fluoride release from Conseal F fissure sealant in different media.
Material And Methods:
Sealant samples were placed in (a) artificial saliva without calcium ions (C++) at pH of 4.5, 5.5, 6.0, 7.0, and 7.5, (b) artificial saliva with calcium ions (Ca") at pH 4.5, and 5.5, (c) saline, and (d) deionized water. Fluoride concentration in solution was measured after 1, 3, 24, 48, 72, and 168 hours from the start of the experiment.
Results:
The highest cumulative fluoride concentration was found in saline (9.39 +/- 2.17 microg F/mm(2)), the lowest in artificial saliva at pH of 7.0 (0.45+/-0.14 microg F/mm(2)). The highest fluoride emission was observed during the first three hours which then decreased to a low but relatively stable level.
Conclusion:
The level of fluoride release from Conseal F fissure sealant depends on composition and pH of the medium. Decrease in pH increased fluoride release. This property is essential for patients with low salivary pH and high risk of caries.

