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Effective obesity treatments.

Lynda H Powell1, James E Calvin, James E Calvin

  • 1Department of Preventive Medicine, Rush University Medical Center, Chicago, IL 60612-3244, USA. lynda_powell@rush.edu

The American Psychologist
|May 2, 2007
PubMed
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Effective obesity treatments, including lifestyle and drug interventions, offer sustained weight loss and health benefits. Combining approaches may provide the best results for diverse patients.

Area of Science:

  • Obesity Medicine
  • Evidence-Based Medicine
  • Public Health

Background:

  • The United States faces an obesity epidemic, prompting policy changes for effective treatments.
  • Medicare now supports evidence-based obesity interventions.

Purpose of the Study:

  • To review randomized trial evidence on the efficacy and safety of lifestyle, drug, and surgical obesity treatments.
  • To assess sustained weight reduction (≥2 years) and associated health benefits.

Main Methods:

  • Systematic review of 9 lifestyle, 5 drug, and 2 surgical randomized trials.
  • Analysis of weight loss, sustainability, and risk-benefit profiles.

Main Results:

  • Lifestyle and drug interventions yielded ~7-lb sustained weight loss over 2 years with improved health markers.

Related Experiment Videos

  • Surgical interventions show potential for significant weight loss in morbidly obese individuals but carry short-term risks.

    • Conclusions:

    • Lifestyle and drug interventions provide modest, safe weight loss with significant clinical benefits.
    • Combined interventions (lifestyle, drug, surgery) may offer the most effective strategy for diverse patient populations.