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Cleveland Clinic PediPump lamb cadaver fitting studies
Faruk Cingoz1, Kiyotaka Fukamachi, Yoshio Ootaki
1Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, USA.
Artificial Organs
|May 2, 2007
Summary
Researchers tested the PediPump, a pediatric ventricular assist device (VAD), in lamb cadavers. Left thoracotomy offered the best fit for both right and left ventricular assist devices (RVAD/LVAD) in the small lamb model.
Area of Science:
- Biomedical Engineering
- Pediatric Cardiology
- Medical Device Development
Background:
- Pediatric heart failure necessitates advanced VAD solutions.
- Current VADs face challenges in pediatric application.
- The PediPump aims to address these limitations.
Purpose of the Study:
- To evaluate the anatomical fit of the PediPump VAD in a pediatric model.
- To determine optimal pump placement and conduit design for chronic implantation.
- To assess feasibility for both right VAD (RVAD) and left VAD (LVAD) configurations.
Main Methods:
- Lamb cadaver models (3.7-34.2 kg) were used for surgical simulation.
- Prototype PediPump RVAD and LVAD were implanted via sternotomy and left thoracotomy.
- Inflow cannula angles and outflow graft configurations were analyzed for optimal fit.
Main Results:
- Sternotomy approach required long inflow cannulas for both RVAD and LVAD.
- Left thoracotomy allowed for better PediPump VAD fitting within the thoracic cavity.
- Specific inflow cannula angles (70° for RVAD, 130° for LVAD) and outflow graft designs were identified.
Conclusions:
- Left thoracotomy is the preferred surgical approach for PediPump implantation in small lamb models.
- Optimized conduit design is crucial for successful chronic VAD implantation in pediatric patients.
- These findings support further development of the PediPump as a pediatric VAD.
