Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Brain and behavior: a task-dependent eye movement study.

M R Burke1, G R Barnes

  • 1Faculty of Life Sciences, University of Manchester, Manchester M60 1QD, UK. m.r.burke@manchester.ac.uk

Cerebral Cortex (New York, N.Y. : 1991)
|May 2, 2007
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Motor Sequence Learning in the Brain: The Long and Short of It.

Neuroscience·2018
Same author

Reconstructing anatomy from electro-physiological data.

NeuroImage·2017
Same author

Dissociation of the rostral and dorsolateral prefrontal cortex during sequence learning in saccades: a TMS investigation.

Experimental brain research·2015
Same author

The contribution of the right supra-marginal gyrus to sequence learning in eye movements.

Neuropsychologia·2013
Same author

Algorithmic procedures for Bayesian MEG/EEG source reconstruction in SPM.

NeuroImage·2013
Same author

Theta oscillations orchestrate medial temporal lobe and neocortex in remembering autobiographical memories.

NeuroImage·2013
Same journal

An expanded cortical map of von Economo neurons in the human medial prefrontal cortex.

Cerebral cortex (New York, N.Y. : 1991)·2026
Same journal

For better and worse: neural self-partner overlap during social feedback is associated with relationship satisfaction and depressive symptoms.

Cerebral cortex (New York, N.Y. : 1991)·2026
Same journal

Regions in the human inferior temporal gyrus are engaged in numerosity processing across visual stimulus categories.

Cerebral cortex (New York, N.Y. : 1991)·2026
Same journal

Differentiation of cortical areas: effects of free energy minimization with broken symmetry.

Cerebral cortex (New York, N.Y. : 1991)·2026
Same journal

Prior exposure to speech rapidly modulates cortical processing of high-level linguistic structure.

Cerebral cortex (New York, N.Y. : 1991)·2026
Same journal

Beta bursts in SMA mediate anticipatory muscle inhibition.

Cerebral cortex (New York, N.Y. : 1991)·2026
See all related articles

This study reveals distinct brain activations for pursuit and saccadic eye movements using fMRI. Pursuit eye movements activate the dorsolateral prefrontal cortex (DLPFC), while saccades engage the frontopolar region.

Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Ophthalmology

Background:

  • Electrophysiological and behavioral studies suggest neurological similarities between pursuit and saccadic eye movements.
  • Previous research indicated bimodal latency distributions for both movement types, with differences in latency and segregation between saccades and pursuit.

Purpose of the Study:

  • To investigate the specific brain areas involved in pursuit and saccadic eye movements.
  • To identify neural correlates of behavior during predictable (PRD) and randomized (RND) visual stimuli presentations.
  • To differentiate brain activity related to velocity-dependent (pursuit) versus position-dependent (saccades) control.

Main Methods:

  • Functional magnetic resonance imaging (fMRI) was employed during equivalent PRD and RND target presentations.

Related Experiment Videos

  • Analysis involved contrasting brain activation patterns between pursuit and saccadic eye movements.
  • Further contrasts examined differences between visually driven (RND) and memory-driven (PRD) responses.

    • Main Results:

    • Pursuit eye movements showed greater activation in the dorsolateral prefrontal cortex (DLPFC) compared to saccades.
    • Saccadic eye movements exhibited higher activation in the frontopolar region relative to pursuit.
    • Visually guided movements (RND) engaged the frontal eye fields more than memory-guided movements (PRD).
    • Memory-guided responses (PRD) showed increased activity in the supplementary eye fields and superior parietal lobe.
    • Learning-related activation during PRD was observed in visual area V5, DLPFC, and cerebellum.

    Conclusions:

    • Distinct neural substrates underlie pursuit and saccadic eye movements, particularly in prefrontal regions.
    • The frontal eye fields, supplementary eye fields, and superior parietal lobe play differential roles in visually versus memory-guided eye movements.
    • Learning processes during predictable target tracking involve visual area V5, DLPFC, and the cerebellum.