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Related Experiment Videos

Light-adjustable lens: customizing correction for multifocality and higher-order aberrations.

Christian A Sandstedt1, Shiao H Chang, Robert H Grubbs

  • 1Calhoun Vision, Inc, Pasadena, California, USA.

Transactions of the American Ophthalmological Society
|May 2, 2007
PubMed
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Customized multifocal and aspheric patterns were successfully created on light-adjustable lenses (LALs) using a digital light delivery (DLD) system. This technology corrects defocus and spherical aberration in vitro and in vivo.

Area of Science:

  • Ophthalmology
  • Optical Engineering
  • Biomedical Engineering

Background:

  • Light-adjustable lenses (LALs) offer adjustable optical properties.
  • Customization of intraocular lenses is crucial for precise vision correction.
  • Digital Light Delivery (DLD) systems provide advanced control over light-based manufacturing.

Purpose of the Study:

  • To assess the feasibility of creating customized multifocal and aspheric patterns on LALs.
  • To utilize a DLD system for precise pattern generation on LALs.
  • To evaluate the simultaneous correction of defocus and spherical aberration.

Main Methods:

  • Silicone LALs were irradiated in vitro using a DLD system with designed spatial intensity patterns.
  • Multifocal optics with customized power and diameter were created.

Related Experiment Videos

  • In vivo adjustments for defocus and spherical aberration were performed in a rabbit model.
  • Optical properties were analyzed using interferometry and wavefront sensing.

    • Main Results:

    • Reproducible customization of multifocal pattern zone diameter and power was achieved in vitro.
    • Bull's-eye bifocal and annular multifocal patterns were successfully fabricated.
    • Spherical aberration was simultaneously reduced with correction of hyperopia and myopia, both in vitro and in vivo.
    • LALs could be readjusted after initial emmetropia adjustment.

    Conclusions:

    • Customized multifocal optics were successfully created on LALs in vitro.
    • Simultaneous correction of defocus and spherical aberration was demonstrated in vitro and in vivo.
    • The potential for correcting higher-order aberrations using this DLD system was shown.