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Persistent placoid maculopathy: a new clinical entity.

Pamela R Golchet1, Lee M Jampol, David Wilson

  • 1Department of Ophthalmology, Northwestern University, Chicago, Illinois, USA.

Transactions of the American Ophthalmological Society
|May 2, 2007
PubMed
Summary
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A new eye condition, persistent placoid maculopathy, resembles serpiginous choroiditis but has a different course. It often leads to choroidal neovascularization and vision loss.

Area of Science:

  • Ophthalmology
  • Retinal Diseases
  • Choroidal Neovascularization

Background:

  • Macular serpiginous choroiditis is a known retinal condition.
  • A distinct clinical entity with similar features was observed.

Observation:

  • Five patients aged 50-68 presented with whitish, plaque-like macular lesions.
  • Lesions involved the macula but spared peripapillary areas.
  • Visual acuity remained good initially despite foveal involvement.

Findings:

  • The condition, termed persistent placoid maculopathy, showed atypical angiographic features.
  • Lesions faded over time, but angiographic findings persisted.
  • Choroidal neovascularization (CNV) developed in 90% of eyes, leading to disciform scars in 70%.

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Implications:

  • Persistent placoid maculopathy is a distinct clinical entity.
  • CNV is a common complication, resulting in central vision loss.
  • Early identification and management of CNV are crucial.