Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Hypertension I: Introduction01:28

Hypertension I: Introduction

Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
Type II Diabetes I: Introduction01:26

Type II Diabetes I: Introduction

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
Diabetic Nephropathy01:28

Diabetic Nephropathy

Definition Diabetic nephropathy is a chronic kidney complication that results from prolonged hyperglycemia.Prevalence It is the most common cause of chronic kidney disease (CKD) and end-stage renal disease (ESRD) worldwide, affecting up to half of individuals with diabetes.Pathophysiology • Sustained hyperglycemia triggers multiple hemodynamic and metabolic changes in the kidney. • Early in the disease, increased renal blood flow and glomerular hyperfiltration occur due to afferent arteriolar...
Factors affecting Blood pressure01:28

Factors affecting Blood pressure

Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Validation of automated whole-body analysis of metabolic and morphological parameters from an integrated FDG-PET/MRI acquisition.

Scientific reports·2020
Same author

Prospective evaluation of long-term safety of dual-release hydrocortisone replacement administered once daily in patients with adrenal insufficiency.

European journal of endocrinology·2014
Same author

Current practice of glucocorticoid replacement therapy and patient-perceived health outcomes in adrenal insufficiency - a worldwide patient survey.

BMC endocrine disorders·2012
Same author

Improved cortisol exposure-time profile and outcome in patients with adrenal insufficiency: a prospective randomized trial of a novel hydrocortisone dual-release formulation.

The Journal of clinical endocrinology and metabolism·2011
Same author

Effects of ramipril and rosiglitazone on cardiovascular and renal outcomes in people with impaired glucose tolerance or impaired fasting glucose: results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial.

Diabetes care·2008
Same author

Risk factors and treatment at recurrent stroke onset: results from the Recurrent Stroke Quality and Epidemiology (RESQUE) Study.

Cerebrovascular diseases (Basel, Switzerland)·2008

Related Experiment Videos

Risk factor identification and assessment in hypertension and diabetes (RIAHD) study.

S Skrtic1, A Niklason, T Leoo

  • 1Section of Clinical Pharmacology, Dept of Internal Medicine, Sahlgrenska University Hospital, Göteborg, Sweden. stanko.skrtic@medic.gu.se

Blood Pressure
|May 3, 2007
PubMed
Summary

The RIAHD study found fibrinogen is a key cardiovascular risk factor in hypertensive patients. Extended risk factor assessment is crucial for accurate hypertension and diabetes management.

Related Experiment Videos

Area of Science:

  • Cardiology
  • Hypertension Research
  • Diabetes Complications

Background:

  • Hypertension and diabetes are major cardiovascular risk factors.
  • Accurate risk assessment is vital for patient management.
  • Novel risk factors require investigation in diverse patient groups.

Purpose of the Study:

  • To identify novel cardiovascular risk factors in hypertensive patients.
  • To compare home versus office blood pressure measurements.
  • To evaluate physician and patient risk assessment accuracy.

Main Methods:

  • Non-interventional study of 699 hypertensive patients (low-risk vs. high-risk).
  • Assessed blood viscosity, inflammatory markers (fibrinogen, hsCRP), and genetic polymorphisms.
  • Compared home blood pressure (BP) with office BP measurements and ESH/ESC SCORE.

Main Results:

  • Fibrinogen levels were significantly higher in the high-risk group.
  • Home systolic BP was lower than office BP in both groups.
  • Physicians underestimated cardiovascular risk in low-risk patients.

Conclusions:

  • Fibrinogen is an important circulating risk factor in hypertension.
  • Home BP monitoring reveals discrepancies with office measurements.
  • Comprehensive risk factor assessment is essential for optimal patient care.