Related Experiment Video
Updated: Jul 15, 2026

Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis
Published on: May 10, 2024
Eosinophilic fasciitis in a 57-year-old Japanese-American woman
Deryll U Ambrocio1, Kristine Uramoto
1Department of Internal Medicine, University of Hawai'i John A. Burns School of Medicine, Honolulu, HI 96813, USA. dambrocio@gmail.com
Abstract:
Eosinophilic fasciitis (EF) is a rare connective tissue disorder characterized by symmetrical sclerodermatous skin changes primarily affecting the extremities and histologically, by thickening of the fascia with chronic inflammatory infiltrate containing eosinophils. EF is associated with peripheral eosinophilia, hypergammaglobulinemia, and an elevated ESR. Reported is a case of EF in a 57-year-old Japanese-American woman who refused treatment with prednisone, review of other treatment options, and discussion of key differences between this disease and scleroderma.
Related Concept Videos
Rocky Mountain Spotted Fever
Asthma III: Clinical Manifestations
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma-II: Pathophysiology and Classification
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Amebiasis
Asthma-III: Symptoms and Complications
Classification of Asthma