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Updated: Jul 15, 2026

A Protocol for Comprehensive Assessment of Bulbar Dysfunction in Amyotrophic Lateral Sclerosis (ALS)
Published on: February 21, 2011
Palliative care in amyotrophic lateral sclerosis, Parkinson's disease, and multiple sclerosis
Lauren B Elman1, David J Houghton, Gregory F Wu
1ALS Association Center, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Background:
Amyotrophic lateral sclerosis, Parkinson's disease, atypical parkinsonian syndromes, and multiple sclerosis are progressive neurologic disorders that cumulatively afflict a large number of people. Effective end-of-life palliative care depends upon an understanding of the clinical aspects of each of these disorders.
Objectives:
The authors review the unique and overlapping aspects of each of these disorders with an emphasis upon the clinical management of symptoms.
Design:
The authors review current management and the supporting literature.
Conclusions:
Clinicians have many effective therapeutic options to choose from when managing the symptoms produced by these disorders.
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