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Related Concept Videos

Epilepsy and Seizures: Overview01:24

Epilepsy and Seizures: Overview

Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Epilepsy ll: Types01:22

Epilepsy ll: Types

Recurrent seizures, stemming from abnormal electrical activity in the brain, are the defining characteristic of epilepsy, a chronic neurological condition. Because seizure features vary greatly, epilepsy is classified using two systems: by seizure type and by epilepsy syndromes. These classifications enable clinicians to describe seizure patterns and select suitable treatment strategies.I. Classification by Seizure Type1. Focal EpilepsyFocal epilepsy begins in one hemisphere of the brain.
Seizures l: Introduction01:20

Seizures l: Introduction

Understanding seizures and epilepsy relies on key definitions that help in recognizing, classifying, and managing these disorders. These definitions provide a framework for recognizing, classifying, and managing seizure disorders.DefinitionsA seizure is a sudden, abnormal burst of electrical activity in the brain that can cause changes in awareness, movement, sensation, or behavior, depending on the area involved. Epilepsy is a chronic condition characterized by recurrent, unprovoked seizures,...
Seizures: Classification01:13

Seizures: Classification

Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:

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Related Experiment Video

Updated: Jul 15, 2026

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe
06:04

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

Published on: August 16, 2024

Developmental outcome after epilepsy surgery in infancy.

Tobias Loddenkemper1, Katherine D Holland, Lisa D Stanford

  • 1Department of Pediatric Neurology, Cleveland Clinic, Cleveland, OH 44195-5245, USA.

Pediatrics
|May 3, 2007
PubMed
Summary

Epilepsy surgery in infants improved seizure control and developmental quotient (DQ). Preoperative DQ and younger age, especially with epileptic spasms, predicted greater DQ gains post-surgery.

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Last Updated: Jul 15, 2026

Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe
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Area of Science:

  • Pediatric Neurology
  • Developmental Neuroscience
  • Epilepsy Surgery Outcomes

Background:

  • Epilepsy surgery in infants (<3 years) is complex.
  • Assessing developmental impact is crucial for this age group.

Observation:

  • Fifty infants (<18 years) underwent epilepsy surgery.
  • Bayley Scales of Infant Development assessed neurodevelopment.
  • Developmental quotient (DQ) was calculated.

Findings:

  • Modest postoperative DQ improvement observed.
  • Preoperative and postoperative DQ correlated well.
  • Younger age and epileptic spasms associated with greater DQ increase.

Implications:

  • Epilepsy surgery can positively impact infant development.
  • Early surgical intervention may be beneficial.
  • Preoperative developmental status is a key predictor of outcome.