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Deep venous thrombosis associated with tuberculosis.

Rahul Naithani1, Neerja Agrawal, Ved P Choudhary

  • 1Department of Hematology, All India Institute of Medical Sciences, New Delhi 110029, India. dr_rahul6@hotmail.com

Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis
|May 3, 2007
PubMed
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Inflammation can cause blood clotting disorders. A young man with deep vein thrombosis was found to have tuberculosis, a condition known to induce hypercoagulability and clotting complications.

Area of Science:

  • Internal Medicine
  • Hematology
  • Infectious Diseases

Background:

  • Inflammation and hemostasis are closely linked, potentially leading to a hypercoagulable state.
  • Hypercoagulable states increase the risk of thromboembolic events.
  • Tuberculosis is a complex infectious disease with potential systemic effects.

Observation:

  • A 34-year-old male presented with recurrent deep vein thrombosis (DVT).
  • Diagnostic workup for secondary causes of DVT was initiated.
  • Tuberculosis was identified as the underlying cause.

Findings:

  • Tuberculosis can induce a hypercoagulable state through various mechanisms.
  • This hypercoagulable state associated with tuberculosis can precipitate thromboembolic complications like DVT.

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  • The patient was successfully treated with anti-tuberculosis medications and anticoagulants.

    • Implications:

    • This case highlights the importance of considering tuberculosis in young patients with unexplained thromboembolic events.
    • Understanding the prothrombotic mechanisms of tuberculosis is crucial for effective patient management.
    • Integrated management involving infectious disease specialists and hematologists is essential for such complex cases.