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Published on: November 9, 2016
Paediatric analgesia in the emergency department, are we getting it right?
Colin Donald1, Russell Duncan, Lorraine Blair
1Accident and Emergency, Ninewells Hospital, Dundee, Scotland, UK. colin.donald@tuht.scot.nhs.uk
Insights
Prescribing paediatric analgesia by age often leads to underdosing. A common weight-estimation formula also underestimates children's weight, potentially causing further underdosing of medications like paracetamol and ibuprofen.
Area of Science:
- Pediatric Emergency Medicine
- Clinical Pharmacology
- Evidence-Based Dosing
Background:
- Accurate dosing of paediatric analgesia is crucial for effective pain management in emergency settings.
- Current prescribing practices for simple analgesics in children often rely on age rather than weight.
Purpose of the Study:
- To quantify dose discrepancies in paediatric analgesia prescribing by comparing age-based versus weight-based dosing.
- To evaluate the accuracy of a common weight-estimation formula for children in a clinical setting.
Main Methods:
- A prospective survey of 247 children receiving paracetamol and/or ibuprofen in UK emergency departments.
- Prescribed doses were compared to optimal weight-based doses; actual weights were compared to formula-estimated weights.
Main Results:
- Age-based dosing resulted in significant underdosing: paracetamol at 67% (P<0.001) and ibuprofen at 51% (P<0.001) of optimal doses.
- The weight-estimation formula [weight kg=2 (age years+4)] underestimated children's weight by 16% (P<0.001).
Conclusions:
- Age-based prescribing of paediatric analgesia frequently leads to substantial underdosing.
- Relying on the tested weight-estimation formula may also contribute to underdosing.
Objectives:
To measure the dose discrepancy in prescribing simple paediatric analgesia, in the emergency department, by comparing age and actual weight-based dosing. To establish the accuracy of the weight-estimation formula for children [weight kg=2 (age years+4)].
Methods:
A prospective survey conducted in the emergency departments of a UK teaching hospital and district general hospital. Two hundred and forty-seven children were prescribed simple analgesia in the form of paracetamol and ibuprofen or both. The dose prescribed was based on age. All children were weighed and a maximum dose based on the child's weight was calculated. The individual child's weight was also compared with the weight calculated using the estimation formula.
Results:
A total of 247 patients were included. Two hundred and thirty-three patients were prescribed paracetamol. Fifteen patients were prescribed ibuprofen. The paracetamol group was administered a mean dose that was 67% (P<0.001) of the optimal dose that was based on weight. Ibuprofen dosage was 51% (P<0.001) of optimal dose. The weight-estimation formula underestimated weight by 16% (P<0.001).
Conclusions:
Prescribing analgesia by age often results in significant underdosing in the paediatric population. Predicting a child's weight using the calculation may result in underdosing.
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