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Updated: Jul 15, 2026

An In Vivo Estrogen Deficiency Mouse Model for Screening Exogenous Estrogen Treatments of Cardiovascular Dysfunction After Menopause
Published on: August 13, 2019
[Concerning the so-called "oestrogenic" smears of the postmenopausal woman]
M Escudero-Fernandez1, E Arderiu-Torne, J Botella-Llusia
1Departemento de Ginecologia, Hospital Clinico, Planta V. Norte Ciudad Universitaria, Madrid 3, Espagne.
Abstract:
The occurrence of oestrogenic smears in postmenopausal women has been reported by several authors. Oestrogenic activity has been examined in 962 smears from postmenopausal women ; these results have been compared with those obtained in 214 cases of surgical menopause. Does the senescent ovary continue to produce oestrogens ? Or are the mucous membranes of the female genital apparatus, and in particular the vaginal mucous membranes, capable of transforming certain 17-CS type suprarenal catabolites into oestrogens. or at least of reactivating these catabolites "oestrogenically".
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