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[Activation of (ADP-ribose) polymerase by DNA fragmented by micrococcal nuclease and DNAase I]

L V Karabashian, A G Mkhitarian, D L Arutiunian

Biokhimiia (Moscow, Russia)

|September 1, 1991

Abstract:

Activation of (ADP-ribose) polymerase by DNA fragments obtained by digestion of calf thymus DNA with micrococcal nuclease and DNAase I was studied. It was found that activation of the enzyme is due to its interaction with the terminal parts of double-stranded DNA fragments, the level of activation being independent of the size of DNA fragments.

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