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Related Experiment Videos

Hepatic damage after danazol treatment.

A Lancia1, F Colella, U Nicolella

  • 1Divisione di Medicina Generale, Ospedale Generale di Zona, Figlie di S. Camillo, Roma, Italy.

The Italian Journal of Gastroenterology
|January 1, 1991
PubMed
Summary

Danazol treatment for fibrocystic breast disease can cause liver damage, as shown by liver histology. Other causes of liver injury were ruled out in this case report.

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Area of Science:

  • Hepatology
  • Endocrinology

Background:

  • Fibrocystic breast disease is a common benign condition.
  • Danazol is a synthetic androgen used for treating endometriosis and fibrocystic breast disease.

Observation:

  • A patient developed liver damage during Danazol therapy.
  • Liver histology was performed to evaluate the damage.

Findings:

  • The liver damage was attributed to Danazol treatment.
  • Other potential causes of liver injury were excluded.

Implications:

  • This case highlights the potential hepatotoxicity of Danazol.
  • Clinicians should monitor liver function in patients receiving Danazol.