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A specific bone marrow edema around the foot and ankle following trauma and immobilization therapy: pattern
Iian Elias1, Adam C Zoga, Mark E Schweitzer
1Thomas Jefferson University Hospital, Department of Orthopaedic Surgery, Rothman Institute, 925 Chestnut Street, Philadelphia, PA 19107, USA. ilan.elias@rothmaninstitute.com
Background:
We describe a characteristic pattern of bone marrow edema about the foot and ankle seen by MRI in patients who have undergone recent immobilization therapy and investigate potential etiologies as well as possible clinical significance.
Methods:
Three reviewers retrospectively evaluated 52 ankle MRI examinations in 18 patients with abnormal signals compatible with bone marrow edema who had been treated with various types and durations of immobilization of the lower limb after traumatic injury. Bone marrow edema patterns were characterized by distribution, extent, location, and interval evolution or resolution on subsequent followup MRI examination. These MRI findings were then correlated with clinical history, symptomatology and treatment regimens.
Results:
All patients had a characteristic pattern of bone marrow edema about the foot and ankle predominating in subchondral, subcortical, and subenthesial locations. The occurrence of this edema pattern was most often noted on MRI within the first 12 weeks after completion of immobilization therapy or resumption of partial or full weightbearing and did not correlate well with new symptomatology or pain. In patients with protracted imaging followup, the bone marrow edema ultimately resolved and was not associated with reported setbacks in recovery course or unexpected delays in restoration of function. All MRI examinations performed more than 18 weeks after the immobilization period showed resolution or stabilization of bone marrow signal, with no continued evolution. No patient had a clinical picture suspicious for reflex sympathetic dystrophy.
Conclusions:
A distinctive pattern of bone marrow edema on MRI of the foot and ankle can be seen on MRI after a variety of weightbearing and nonweightbearing immobilization therapies. This pattern has a consistent appearance on MRI and does not seem to be related to clinical symptomatology. At present, no substantial conclusions can be made regarding the etiology of this phenomenon. However, these bone marrow signal alterations should not mandate further imaging or a change in therapy on the basis of MRI findings alone.
Insights
A specific bone marrow edema pattern on foot and ankle MRI is common after immobilization. This MRI finding is typically transient and does not indicate new symptoms or affect recovery.
Area of Science:
- Radiology
- Orthopedics
- Musculoskeletal Imaging
Background:
- MRI reveals a characteristic bone marrow edema pattern in the foot and ankle following immobilization therapy.
- Investigated potential causes and clinical significance of this post-immobilization MRI finding.
Purpose of the Study:
- To describe and analyze a specific bone marrow edema pattern observed on MRI in patients after lower limb immobilization.
- To correlate MRI findings with clinical presentation, treatment, and recovery outcomes.
Main Methods:
- Retrospective review of 52 ankle MRI examinations in 18 patients treated with immobilization for traumatic injuries.
- Characterization of bone marrow edema patterns (distribution, extent, location, evolution) and correlation with clinical data.
Main Results:
- A consistent bone marrow edema pattern was observed, predominantly in subchondral, subcortical, and subenthesial locations.
- Edema was most frequent within 12 weeks of immobilization completion or weight-bearing resumption, not correlating with new symptoms.
- Bone marrow edema resolved over time without impacting recovery or function; no cases suggested reflex sympathetic dystrophy.
Conclusions:
- A distinct bone marrow edema pattern on foot and ankle MRI is a recognized finding after immobilization therapies.
- This pattern appears consistent, generally unrelated to clinical symptoms, and resolves without intervention.
- Further imaging or treatment changes based solely on this MRI finding are not currently warranted.
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